Treatment of extramammary Paget disease. With special reference to margin width and regional lymphonode dissection.

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Extramammary Paget Disease: Minimal Surgical Therapy

BACKGROUND Extramammary Paget disease (EMPD) is an uncommon malignant neoplasm affecting apocrine gland-bearing skin which usually occurs in the anogenital area of patients older than 50 years. Although Mohs micrographic surgery (MMS) is recommended for the treatment of EMPD, wide local excision has also been performed by many other surgeons including dermatosurgeons. However, the extent of an ...

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Extramammary Paget disease (EMPD) is an uncommon malignancy. It manifests either in the primary form in the skin as an intraepithelial neoplasm, or in secondary form as pagetoid (intraepithelial) spread of an underlying internal carcinoma to the skin. Although local invasion and recurrence of primary extramammary Paget disease are relatively frequent, widespread metastases are rare. As such, th...

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d ry s a sts treatment option for this disease. In 2009 we reported th results obtained in the treatment of 3 cases of EMPD of th vulva with clinical and pathologic features similar to thos described by Hiraldo-Gamero.2 The 3 patients, aged 66, 58, and 82 years, had vulva lesions up to 5 cm in diameter (Fig. 1). In all 3 cases, th results of multiple biopsies (Fig. 2) revealed exclusive intraep...

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ژورنال

عنوان ژورنال: Skin Cancer

سال: 1990

ISSN: 1884-3549,0915-3535

DOI: 10.5227/skincancer.5.85